19 Dec Neuropathy Relief Center of Miami Research Review: Emerging Nonpharmacologic Interventions to Treat Diabetic Peripheral Neuropathy
● Both exercise and consuming a ketogenic diet induce systemic and cellular changes that collectively improve complications associated with DPN. Both interventions may involve similar signaling pathways and benefits but also impact DPN through unique mechanisms.
● Overall, these two interventions have the potential to provide meaningful relief for patients with DPN and provide new avenues to identify new therapeutic targets.
Significance: Diabetic peripheral neuropathy (DPN), a complication of metabolic syndrome, type I, and type II diabetes, leads to sensory changes that include slow nerve conduction, nerve degeneration, loss of sensation, pain, and gate disturbances. These complications remain largely untreatable, although tight glycemic control can prevent neuropathy progression.
Nonpharmacological approaches remain the most impactful to date, but additional advances in treatment approaches are needed.
Recent advances: This review highlights several emerging interventions, including a focus on dietary interventions and physical activity that continue to show promise for treating DPN. We provide an overview of our current understanding of how exercise can improve aspects of DPN.
We also highlight new studies in which a ketogenic diet has been used as an intervention to prevent and reverse DPN.
Critical issues: Both exercise and consuming a ketogenic diet induce systemic and cellular changes that collectively improve complications associated with DPN. Both interventions may involve similar signaling pathways and benefits but also impact DPN through unique mechanisms.
Future directions: These lifestyle interventions are critically important as personalized medicine approaches will likely be needed to identify specific subsets of neuropathy symptoms and deficits in patients and determine the most impactful treatment. Overall, these two interventions have the potential to provide meaningful relief for patients with DPN and provide new avenues to identify new therapeutic targets.
Peripheral neuropathy is a serious diabetes complication and is estimated to affect up to 80% of people with diabetes. The feet are the most common area of the body where the nerves are damaged as a result of high blood sugar resulting in the need for peripheral neuropathy treatment.
If you have been diagnosed with peripheral neuropathy or have neuropathy symptoms such as pain, burning, numbness in your arms, hands, legs or feet. Please contact us at (305) 275-7475 to schedule and discuss your questions with our new patient specialist or message us your number/email and our team member will reach out to you for scheduling.
Out of town patients can schedule a complimentary Zoom Meeting Consultation or Phone Consultation with Dr. Alfonso. Please contact either by website, email, or by phone if you have any questions. We are here to help you overcome peripheral neuropathy and get you back to enjoying life! You can beat peripheral neuropathy without drugs or surgery!
For more info on the Dr. Alfonso Neuropathy Treatment Protocol please visit our treatment page of our website.
I look forward to meeting and helping you!
Sincerely Yours for Health,
Dr. Rodolfo Alfonso, D.C.
8585 Sunset Drive,
Miami, FL 33143